The selection of a specialty pharmacy should be based on its capacity to address each specialty drug’s unique requirements, to provide comprehensive, quality clinical services to patients, and to meet manufacturers and providers’ data and utilization review needs. Making the correct decision affects all stakeholders, including patients, physicians, and payers, and has long-term implications. Customer satisfaction, adherence, access to specialty drugs, cost containment and waste management can all be positively shaped by partnering with the right specialty pharmacy.